Dr. Enoch – Google Scholar
Dr. Enoch – Scopus
PROFILE SUMMARY
Bio-sketch
Dr. Israel V. Muthu Vijayan Enoch
Hailing from the picturesque village Nazareth near Tirunelveli in Tamil Nadu, Dr. Enoch had his initial schooling in Margoschis Higher Secondary School and undergraduate education in Nazareth Margoschis College. He graduated with M.Sc. Organic Chemistry and M.Phil. from Annamalai University, Chidambaram. Dr. Enoch worked with Prof. M. Swaminathan in Annamalai University and earned doctorate in the year 2005. In addition, he earned M.Tech. Nanotechnology from Anna University of Technology, Coimbatore. For his postdoctoral research, Dr. Enoch worked with Prof. Yves Mely, University of Louis Pasteur, France. Dr. Enoch is a veteran in teaching with 14 years of experience. He has instructed students of B.E/B.Tech, B.Sc. Chemistry, M.Sc. Chemistry, M.Sc. Organic Chemistry, M.Sc. Nanoscience & Technology, and M.Tech. Nanotechnology. He extended an active contribution to the design of the M.Sc. programme in Nanoscience & Technology and its programme structure, and curriculum and syllabi. Dr. Enoch has published more than 110 articles in reputed scientific journals mostly as either the first or corresponding author. He has presented papers in an impressive number of conferences. A major project funded by the Department of Science and Technology, Government of India, has been successfully completed by him. At present, a major project funded by the Department of Atomic Energy-Board of Research in Nuclear Sciences, is under progress with Dr. Enoch as the principal investigator. Nine doctoral scholars have graduated under his direct supervision and three reporting to his joint-supervision. He has guided two M.Phil. students (in Chemistry/Nanoscience & Technology) and more than 30 students in their Masters’ thesis. Six post-graduates are currently doing Ph.D under his supervision. Dr. Enoch’s research interests are on magnetic and luminescent nanomaterials for cancer drug targeting, supramolecular host-guest chemistry, and drug-DNA interactions.
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EDUCATION
2011 – M.Tech. (Nanotechnology)
Anna University of Technology, Coimbatore.
2005 – PhD (Chemistry)
Annamalai University, Tamil Nadu.
2001 – M.Phil. (Chemistry)
Annamalai University, Tamil Nadu.
1999 – M.Sc. (Organic Chemistry)
Annamalai University, Tamil Nadu.
1997 – B.Sc. (Chemistry)
Nazareth Margoschis College, Manonmanium Sundaranar University, Tamil Nadu.
CORE COMPETENCIES
- Academics Administration
- Education Leadership
- Discipline & Coordination
- Research and Development
- Performance Evaluations
- Education Standards & Policies
- Meetings & Assessments
- Students Management
- Cross-functional Coordination
- Curriculum Design & Development
- Teaching & Tutoring
- Training & Development
ACADEMIC RESEARCH
Postdoctoral
Molecular Mechanism of the Chaperone Activity of Hepatitis C Viral Core Protein.
Ph.D
Photophysical and Photoprototropic Behavior of Organic Fluorophores in β-Cyclodextrin.
M.Phil
Synthesis and Antibacterial Activity of some 4, 6-Diaryl-5-azaindazolin-3- ones.
M.Tech.
Self-assembly directed synthesis of nanostructure: Formation of host– guest complex of a heterocycle with β-Cyclodextrin and its assembly on gold nanoparticles.
ACHIEVEMENTS
Regular Research Project Scheme (2018 – 2021) funded by the Department of Atomic Energy, Board of Research in Nuclear Sciences, BARC, Mumbai (21.7 lakh Rupee Project)
Porphyrin-tethered-β-cyclodextrin loaded with guanidinobenzimidazoles as G-quadruplex DNA binders” (37(2)/14/17/2018-BRNS)
Research Excellence Award in 2018 from Institute of Scholars
Fast track scheme for young scientists (2010 – 2014) funded by the Department of Science of Technology, New Delhi (A 18.91 lakh rupee project under the scheme)
Host–guest association of some coumarins and flavones with the self-assembled nanocapsule of C-hexylpyrogallol [4]arene” (SR/FT/CS-062/2009)
Best Researcher Award in 2015 from Karunya Institute of Technology & Sciences
Karunya Short Term Research Grant (2008 – 2009) Karunya Institute of Technology and Sciences (A 45,000 rupee project) “Chemico-biological interaction of the phyto-constituents of curculigo orchioides gatern with Bovine Serum Albumin
Chilean Government’s Funding Agency
Reviewer of Funded Projects of the Chilean Government’s Funding Agency, ‘Comisiόn Nacional de Investigaciόn Cientificay Tecnόlogica – CONICYT’
Research Award Review Panel – Expert Member of the Review Panel for the ‘Best Researcher Award’ at National Level in Nehru College of Engineering and Technology in the Year 2014
Patent Filed:
I. V. M. V. Enoch, A. Alexander, A Composition for Preparing Electrospun Polymeric Nanofiber Mat For Preparing Face Mask For Antimicrobial Use, Vide Patent Application No. 202041024059, Dated 08.06.2020, Indian Patent
Indian Government’s Funding Agency – Reviewer of Funded Projects of the Indian Government’s Funding Agency, Department of Science and Technology – Science and Engineering Research Board.
INSTRUMENTAL TECHNIQUES
- Solid-phase Peptide Synthesis
- Fluorescence Confocal Microscopy
- Fluorescence correlation spectroscopy
- Sub-micron particle analyzing
- High-Performance Liquid Chromatography
- Surface Plasmon Resonance Biosensor
- Atomic Force Microscopy
- Scanning Tunneling Microscopy
- Scannning Electron Microscopy
- Photoluminescence
- FT-IR spectroscopy
- 1H–1H COSY NMR spectroscopy
- NOESY NMR spectroscopy
- 2D ROESY NMR
- 2D DOSY NMR spectroscopy
- X-Ray Photoelectron Spectroscopy
- Powder X-Ray DiCraction
- Vibrating Sample Magnetometry
- Superconducting Quantum Interference
- Thermogravimetric & Raman Spectroscopic Analysis
WORK EXPERIENCE
- Since – Jul’08:
Karunya Institute of Technology and Sciences.
- Jan’08 – Jun’08:
Karpagam Arts and Science College as Senior Lecturer.
- Dec’06 – Dec’07:
University of Louis Pasteur, France as Postdoctoral Fellowship – Biophysical Chemistry.
- Jun’05 – Dec’06:
Muthayammal College of Arts and Science as Lecturer
- Aug’04 – May’05:
SCAD College of Engineering and Technology as Lecturer
Key Result Areas :
- Heading the Centre for Nanoscience & Genomics, Teaching, Research and Mentoring students
- Assisting 6 PhD students and 2 M.Sc. (Nanoscience & Technology) students in their project work
- Delivering lectures to students and ensured proper knowledge transfer through a range of sessions
- Assessing curriculum, teaching methods & programs to determine their effectiveness and efficiency
- Enclosing exercises, questionnaires and assignments for students at various levels, responding to the queries in a spontaneous manner and setting & marked assignments and tests
- Aligning student’s interests with potential opportunity careers to guide students in effective decision-making regarding their career direction and future fields of study
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CONFERENCES
- National Conference on Molecules to Materials: Solving the problems of Mankind, Karunya University, Coimbatore, 15th &16th February, 2013. (2nd Best paper award)
- Regional Science Congress on Science for Shaping the Future of India, (National conference) Kongunadu Arts & Science College (Autonomous) Coimbatore, 15th to 16th Dec’12
- National Workshop on Advanced Instrument for Characterization, Bharathiar University, Coimbatore, 27th March, 2012
- National level seminar on Bioinformatics, Bharathiar University, Coimbatore, 30th September, 2011
- Recent Developments in Medicinal and green chemistry, Karpagam University, Coimbatore, 4th and 5th Mar’10 (National Conference)
- Presented a paper in UGC National Seminar on Current Trends in Chemistry, Department of Chemistry, Annamalai University, Chidambaram, held on 24th and 25th Mar’04
- Presented a paper in UGC National Seminar on Chemical Physics, Department of Physics, Annamalai University, held on 10th and 11th Mar’03
- Presented a paper in AICTE National Seminar on Pharmaceutical Sciences and Technology Today, Annamalai University, held on 13th and 14th Sep’01
- Multidisciplinary Frontiers of Medicinal Chemistry: Synthesis, Molecular Biology & Technology, (International conference) SASTRA University, Thanjavur, 18 & 19th Jan’13
- National Seminar on Perspectives and Issues in Structural Biology (MOTIF’12), Bharathiar University, Coimbatore, 19th October, 2012, (Best paper award, 1st prize)
- Recent advances in computer aided drug designing, Malabar Christian College, Calicut, 23rd and 24th March, 2011. (National conference)
- International Symposium on Innovations in Free radical Research and Experimental Therapeutics, Karunya University, Coimbatore, 7th to 9th Dec’11 (Best paper award, 1st prize)
- Presented a paper in National Seminar on Nanomaterials, Department of Physics, Karunya University, Karunya nagar, held on 17th and 18th Oct’08
- Attended One-day Workshop on Patent Awareness, Faculty of Engineering and Technology, Annamalai University, held on 14th Apr’04
- Presented a paper in 39th Annual Convention of Chemists 2002, conducted by Indian Chemical Society, at Nagarjuna University, Andhra Pradesh, between 22nd and 26th Dec’02
- Attended Haggai Institute Seminar for Advanced Leadership Skills, Chidambaram, held between 1st and 3rd Feb’02
OUR LAB
PHOTOS
The research of Dr. Enoch’s group is centered on Biomedical Nanotechnology. Currently, the research interests are on Cyclodextrin Host : Guest Chemistry, Magnetic Nanomaterials for Targeted Drug Delivery, Oligosachcharide-Tethered Polymers, and Supramolecular Interaction of Small Molecule Ligands with G-quadruplexes. These include chemical synthesis, physical and chemical methods of nanomaterials synthesis, spectroscopi and analytical science, and bio-assays that fall at the interface of Materials Science, Nanochemistry, and Biology.
REPRESENTATIVE PUBLICATIONS
Affinity variation in the interactions of tryptophan- ß-cyclodextrin-platinum complex with G-quadruplex and duplex DNAs
A. Muruganantham, A. N. D. Sahayam, S. Suganthi, A. Alexander, A. S. Pillai, I. V. M. V. Enoch* Journal of Biomolecular Structure and Dynamics, 2022.
Magnetic hydroxyapatite nanomaterial–cyclodextrin tethered polymer hybrids as anticancer drug carriers
S. Ramasamy, D. Dhamecha, K Kiruthiga, A. S. Pillai, A. Alexander, D Premnath, J. Menon,*I. V. M..V Enoch* Materials Advances, 2021, 2, 3315-3327.
ß-Cyclodextrin-folate functionalized poly(lactic-co-glycolide)–superparamag- netic ytterbium ferrite hybrid nanocarrier for targeted delivery of camptothecin
K. Kaliyamoorthy, A. S. Pillai, A. Alexander, A. Arivarasu, I. V. M. V. Enoch,* S. Ramasamy
Materials Science and Engineering C, 2021, 122, 111796.
Designed poly(ethylene glycol) conjugate-erbium doped magnet- ic nanoparticle hybrid carrier: Enhanced activity of anticancer drug
K. Kaliyamoorthi, A. S. Pillai, A. Alexander, S. Ramasamy, A. Arivarasu, I. V. M. V. Enoch* Journal of Materials Science, 2021, 56, 3925-3934.
Effect of magnetic field on the thermophysical properties of low-density ferro- fluid with diskshaped MgFe²O4 nanoparticles
K. Ajith Archana Sumohan Pillai, I. V. M. V. Enoch, A. B. Solomon* Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 613.
Novel supramolecular ß-cyclodextrin-piperidin-4-one complex assembled on gold nanoparticles. Selective detection of Cd2+ ions
P. Sumathi, S. Suganthi, R. Sivaraj, G. T. Selvan, P. M. Selvakumar, I. V. M. V. Enoch* Microchemical Journal, 2019, 150, 104066.
5-Fluorouracil loaded ß-cyclodextrin-carrying polymeric poly(methylmethacry- late)-coated samarium ferrite nanoparticles and their anticancer activity
M. S. Hariharan, R. Sivaraj, S. Ponsubha, R. Jagadeesh, I. V. M. V. Enoch* Journal of Materials Science, 2019, 54, 4942–4951.
Differential metal ion sensing by an antipyrine derivative in aqueous and ß-cy- clodextrin media: Selectivity–tuning by ß-cyclodextrin
G. T. Selvan, S. Poomalai, S. Ramasamy, P. M. Selvakumar, I. V. M. V. Enoch,* S. G. Lanas,
Andrea Melchior*
Analytical Chemistry, 2018, 90, 13607–13615.
Molecular Encapsulator–Appended Poly(Vinyl Alcohol) Shroud on Ferrite Nanoparticles. Augmented Cancer–Drug Loading and Anticancer Property
R. Selvam, S. Ramasamy, S. Mohiyuddin, I. V. M. V. Enoch,* P. Gopinath,* D. Filimonov*
Materials Science and Engineering C, 2018, 93, 125–133.
Folate-molecular encapsulator–tethered biocompatible polymer grafted with magnetic nanoparticles for augmented drug delivery
R. Sivaraj, S. R. J. Rajkumar, I. V. M. V. Enoch* Artificial Cells, Nanomedicine, and Biotechnology, 2018, 46, 675–682.
Molecular encapsulator on the surface of magnetic nanoparticles. Controlled drug release from calcium ferrite / cyclodextrin–tethered polymer hybrid
R. Sivaraj, S. Beniya, R. Helfried, M. S. A. M. Nadar, I. V. M. V. Enoch,* P. Kay*
Colloids and Surfaces B: Biointerfaces, 2018, 161, 347–355.
Synergistic effect of LDH in the presence of organophosphate on thermal and flammable properties of an epoxy nanocomposite
P. K. Kaul, A. J. Samson, G. T. Selvan, I. V. M. V. Enoch, P. M. Selvakumar
Applied Clay Science, 2017, 135, 234–243.
Binding of 6-methyl-3-phenyliminomethyl-4H-chromen-4-one with bovine se- rum albumin in free and ß-cyclodextrin-complexed forms: Modulation of the
binding by ß-cyclodextrin
S. Chandrasekaran, N. Sudha, D. Premnath, I. V. M. V. Enoch* Journal of Molecular Liquids, 2016, 222, 398–406.
Loading of atorvastatin and linezolid in ß-cyclodextrin–conjugated cadmium selenide / silica nanoparticles: A spectroscopic study
E. J. Antony, A. Shibu, S. Ramasamy, M. S. Paulraj, I. V. M. V. Enoch* Materials Science and Engineering C, 2016, 65, 194–198.
On the accessibility of surface–bound drugs on magnetic nanoparticles. En- capsulation of drugs loaded on modified dextran–coated superparamagnetic
iron oxide by ß-cyclodextrin
N. Sudha, S. Yousuf,* I. V. M. V. Enoch,* M. S. Paulraj, P. Dhanaraj
Colloids and Surfaces B: Biointerfaces, 2016, 141, 423–428.
Loading of atorvastatin and linezolid in ß-cyclodextrin–conjugated cadmium selenide / silica nanoparticles: A spectroscopic study
E. J. Antony, A. Shibu, S. Ramasamy, M. S. Paulraj, I. V. M. V. Enoch* Materials Science and Engineering C, 2016, 65, 194–198.
Mode of encapsulation of Linezolid by ß-Cyclodextrin and its role in Bovine Serum Albumin binding
S. Chandrasekaran, N. Sudha, Y. Sameena, I. V. M. V. Enoch* Carbohydrate Polymers, 2015, 115, 589–597.
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